Born and raised in Leningrad. He received musical education at the Leningrad State Conservatory. M.A.Riemsky-Korsakov in the class of his mother - an aristotle, Honored Artist of Russia Lidia Alexandrovna Gordzevich. He began his career at the age of 18 on the position of soloist-harpist in the orchestra of the musical-drama theater of Karelia in Petrozavodsk.
In the year of graduation from the conservatory, he was recruited to the State Symphony Orchestra of Ukraine, where he has been working since January 1966. Since the first years of his life, Natalia Vasilievna has been active in creative activity - he performs many concerts, performs recordings at the Ukrainian Radio Foundation and on the melodies of the Melody company. Many contemporary Ukrainian composers have written works for the harp with the dedication of N.Izmayilov: G.Lyashenko - Concert and plays for harp solo, Y.Ishchenko - Quintet with harp, Concert for harp and chimball, Sonata for harp solo, V.Guba - Duet for violin and harp; Y. Stankovych - Plays and others.
Natalia Izmaylova and the ensemble of ancient music "Harmony" combines many years of creative communication. Together with the ensemble, the harpist performed recordings, toured cities of Russia, Ukraine, Estonia, Lithuania, Latvia, Germany, the Czech Republic, and other countries.
An indication of the wide educational activity of the artist of the last time is her solo performances in various concert programs for students and students. She also participates in numerous festivals, both as a soloist and in various ensembles.
In 1978, she was awarded the title of Honored Artist of Ukraine, and in December 2008, Natalia Izmaylova's high professional skills and fruitful creative work was awarded the title of People's Artist of Ukraine.